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Microbial toxins : ウィキペディア英語版
Microbial toxins

Microbial toxins are toxins produced by micro-organisms, including bacteria and fungi. Microbial toxins promote infection and disease by directly damaging host tissues and by disabling the immune system. Some bacterial toxins, such as ''Botulinum'' neurotoxins, are the most potent natural toxins known. However, microbial toxins also have important uses in medical science and research. Potential applications of toxin research include combating microbial virulence, the development of novel anticancer drugs and other medicines, and the use of toxins as tools in neurobiology and cellular biology.
==Bacterial toxin==
Bacteria generate toxins which can be classified as either exotoxins or endotoxins. Exotoxins are generated and actively secreted; endotoxins remain part of the bacteria. Usually, an endotoxin is part of the bacterial outer membrane, and it is not released until the bacterium is killed by the immune system. The body's response to an endotoxin can involve severe inflammation. In general, the inflammation process is usually considered beneficial to the infected host, but if the reaction is severe enough, it can lead to sepsis.
Some bacterial toxins can be used in the treatment of tumors.
Toxinosis is pathogenesis caused by the bacterial toxin alone, not necessarily involving bacterial infection (e.g. when the bacteria have died, but have already produced toxin, which are ingested). It can be caused by ''Staphylococcus aureus'' toxins, for example.〔 Page 348 in: 〕

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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